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Quantitative analyses from the factor composition indicated high purity in the synthesized substances, although the scope of the synthesis was also small to think about the substances as Qualified reference resources for determining purity.
The pyrolysed type of UR-a hundred and forty four (UR-a hundred and forty four degradant) displays a four-fold greater agonist exercise with the CB1 receptor and augments the hypothermic and akinetic actions in mice when compared to the parent, indicating that cigarette smoking the drug may possibly augment the pharmacological effects on the central anxious system. In other animal studies, UR-one hundred forty four substitutes with the discriminative stimulus effects of THC in rats, and likewise in mice, effects which can be blocked by the CB1 receptor antagonist, rimonabant.
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